MolNFT v1 · #265324 · protein
AlphaFold monomer V2.0 prediction for nickel-binding periplasmic protein (P33590)
P33590: “AlphaFold monomer V2.0 prediction for nickel-binding periplasmic protein (P33590)”. 5 pockets (best druggability 0.67). MolNFT v1 #265324 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P33590
- Type
- protein
- Length
- 524 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- Nickel-binding periplasmic protein
- UniProt
- P33590
- Pockets
- 5 · best druggability 0.67
Structure
1 distinct chain · 29% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nickel-binding periplasmic protein | protein | 524 | 29% helix, 23% strand | P33590 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.67 | 0.96 | 24 | empty |
| 2 | 530 | 0.63 | 0.75 | 53 | empty |
| 3 | 65 | 0.57 | 0.88 | 23 | empty |
| 4 | 88 | 0.51 | 0.83 | 20 | empty |
| 5 | 93 | 0.34 | 0.74 | 16 | empty |
Compared structures
- 1UIU · Crystal structures of the liganded and unliganded nickel binding protein nika from… · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 1UIU · Crystal structures of the liganded and unliganded nickel binding protein NikA from… · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 2NOO · Crystal Structure of Mutant NikA · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2NOO · Crystal structure of mutant nika · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 4DCY · X-ray structure of NikA in complex with Fe(1S,2S)-N,N-kappa-Bis(2-pyridylmethyl)-N-carboxy… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4DCY · X-ray structure of nika in complex with FE(1S,2S)-N,N-kappa-BIS(2… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4I9D · X-ray structure of NikA in complex with Fe-N,N'-Bis(2-pyridylmethyl)-N-carboxymethyl-N'-me… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4I9D · X-ray structure of nika in complex with fe-N,N'-BIS(2-pyridylmethyl)… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 5ON1 · Crystal structure of NikA in complex with hydroxylated Fe-L1… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 5ON1 · Crystal structure of nika in complex with hydroxylated fe-L1 (N-(2… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 3MVY · X-ray structure of the diatomic oxo-intermediate NikA/1-Int', prior hydroxylation · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 3MVY · X-ray structure of the diatomic oxo-intermediate NIKA/1-int', prior hydroxylation · an experimental structure of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33590
- Elsewhere: UniProt P33590 · AlphaFold DB P33590
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