MolNFT v1 · #263670 · protein
AlphaFold monomer V2.0 prediction for nuclear factor related to kappa-B-binding protein (Q6P4R8)
Q6P4R8: “AlphaFold monomer V2.0 prediction for nuclear factor related to kappa-B-binding protein (Q6P4R8)”. 5 pockets (best druggability 0.67). MolNFT v1 #263670 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6P4R8
- Type
- protein
- Length
- 1,299 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb64DEeDEE372f6B93106C4D05EA5568323EeD16E
- Molecule
- Nuclear factor related to kappa-B-binding protein
- UniProt
- Q6P4R8
- Pockets
- 5 · best druggability 0.67
Structure
1 distinct chain · 25% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear factor related to kappa-B-binding protein | protein | 1299 | 25% helix, 4% strand | Q6P4R8 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.67 | 0.91 | 19 | empty |
| 2 | 220 | 0.47 | 0.73 | 22 | empty |
| 3 | 91 | 0.44 | 0.79 | 17 | empty |
| 4 | 75 | 0.32 | 0.74 | 15 | empty |
| 5 | 80 | 0.29 | 0.72 | 16 | empty |
Compared structures
- 4WLP · Crystal structure of UCH37-nfrkb inhibited deubiquitylating complex · an experimental structure of the same protein · chain A against B, TM-score 0.09
- 3U21 · Crystal structure of a Fragment of Nuclear factor related to kappa-B-binding protein… · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 3U21 · Crystal structure of a fragment of nuclear factor related to kappa-B- binding protein… · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 4UF5 · Crystal structure of UCH-L5 in complex with inhibitory fragment of INO80G · an experimental structure of the same protein · chain A against B, TM-score 0.08
- 4UF5 · Crystal structure of uch-L5 in complex with inhibitory fragment of INO80G · an experimental structure of the same protein · chain A against B, TM-score 0.08
- 4UF6 · UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 4UF6 · Uch-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G · an experimental structure of the same protein · chain A against C, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6P4R8
- Elsewhere: UniProt Q6P4R8 · AlphaFold DB Q6P4R8
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