UniProt Q6P4R8
Nuclear factor related to kappa-B-binding protein (Q6P4R8)
Nuclear factor related to kappa-B-binding protein (UniProt Q6P4R8): 7 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6P4R8
- Protein
- Nuclear factor related to kappa-B-binding protein
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
8 records of Q6P4R8 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3U21 | Crystal structure of a Fragment of Nuclear factor related to kappa-B-binding protein (residues… | x-ray diffraction | A, B | — | — |
| 3U21 | Crystal structure of a fragment of nuclear factor related to kappa-B- binding protein (residues… | x-ray diffraction | A, B | — | — |
| 4UF5 | Crystal structure of UCH-L5 in complex with inhibitory fragment of INO80G | x-ray diffraction | B | — | — |
| 4UF5 | Crystal structure of uch-L5 in complex with inhibitory fragment of INO80G | x-ray diffraction | B | — | — |
| 4UF6 | UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G | x-ray diffraction | C, F, I, L | — | — |
| 4UF6 | Uch-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G | x-ray diffraction | C, F, I, L | — | — |
| 4WLP | Crystal structure of UCH37-nfrkb inhibited deubiquitylating complex | x-ray diffraction | B | — | — |
| Q6P4R8 | AlphaFold monomer V2.0 prediction for nuclear factor related to kappa-B-binding protein (Q6P4R8) | predicted | A | — | 5 (best 0.67) |
Experiment against prediction
- 3U21 chain A against the predicted model Q6P4R8: TM-score 0.97, RMSD 0.97 Å
- 3U21 chain A against the predicted model Q6P4R8: TM-score 0.97, RMSD 0.97 Å
- 3U21 chain B against the predicted model Q6P4R8: TM-score 0.96, RMSD 1.11 Å
- 3U21 chain B against the predicted model Q6P4R8: TM-score 0.96, RMSD 1.11 Å
- 4WLP chain B against the predicted model Q6P4R8: TM-score 0.92, RMSD 1.28 Å
- 4UF5 chain B against the predicted model Q6P4R8: TM-score 0.88, RMSD 1.50 Å
- 4UF5 chain B against the predicted model Q6P4R8: TM-score 0.88, RMSD 1.50 Å
- 4UF6 chain I against the predicted model Q6P4R8: TM-score 0.78, RMSD 1.25 Å
- 4UF6 chain I against the predicted model Q6P4R8: TM-score 0.78, RMSD 1.25 Å
- 4UF6 chain C against the predicted model Q6P4R8: TM-score 0.78, RMSD 1.27 Å
Elsewhere
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