MolNFT v1 · #263630 · protein

AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P100 subunit (Q9WTK5)

Q9WTK5: “AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P100 subunit (Q9WTK5)”. 2 pockets (best druggability 0.58). MolNFT v1 #263630 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9WTK5
Type: protein
Length: 899 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xAa9dfA3b561daFBbf7989Ffd418937f79dC2347c
Molecule: Nuclear factor nf-kappa-B P100 subunit
UniProt: Q9WTK5
Pockets: 2 · best druggability 0.58

Structure

1 distinct chain · 31% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear factor nf-kappa-B P100 subunit	protein	899	31% helix, 12% strand	Q9WTK5

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	196	0.58	0.81	25	empty
2	100	0.31	0.72	17	empty

Compared structures

3JV6 · Crystal structure of the dimerization domains P52 and relb · an experimental structure of the same protein · chain A against B, TM-score 0.12
3JV6 · Crystal structure of the dimerization domains p52 and RelB · an experimental structure of the same protein · chain A against B, TM-score 0.12
3JV5 · Crystal structure of the dimerization domains P52 homodimer · an experimental structure of the same protein · chain A against A, TM-score 0.12
3JV5 · Crystal structure of the dimerization domains p52 homodimer · an experimental structure of the same protein · chain A against A, TM-score 0.12

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9WTK5
Elsewhere: UniProt Q9WTK5 · AlphaFold DB Q9WTK5

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