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AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P100 subunit (Q9WTK5)

Analyse AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P100 subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9WTK5
Type
protein
Length
899 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xAa9dfA3b561daFBbf7989Ffd418937f79dC2347c
Molecule
Nuclear factor nf-kappa-B P100 subunit
UniProt
Q9WTK5
Pockets
2 · best druggability 0.58

Structure

1 distinct chain · 31% helix, 12% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear factor nf-kappa-B P100 subunitprotein89931% helix, 12% strandQ9WTK5

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11960.580.8125empty
21000.310.7217empty

Compared structures

  • 3JV6 · Crystal structure of the dimerization domains P52 and relb · an experimental structure of the same protein · chain A against B, TM-score 0.12
  • 3JV6 · Crystal structure of the dimerization domains p52 and RelB · an experimental structure of the same protein · chain A against B, TM-score 0.12
  • 3JV5 · Crystal structure of the dimerization domains P52 homodimer · an experimental structure of the same protein · chain A against A, TM-score 0.12
  • 3JV5 · Crystal structure of the dimerization domains p52 homodimer · an experimental structure of the same protein · chain A against A, TM-score 0.12

Analyse

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