MolNFT v1 · #263417 · protein
AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells, cytoplasmic 3 (Q12968)
Q12968: “AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells, cytoplasmic 3 (Q12968)”. 3 pockets (best druggability 0.43). MolNFT v1 #263417 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q12968
- Type
- protein
- Length
- 1,075 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Nuclear factor of activated T-cells, cytoplasmic 3
- UniProt
- Q12968
- Pockets
- 3 · best druggability 0.43
Structure
1 distinct chain · 4% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear factor of activated T-cells, cytoplasmic 3 | protein | 1075 | 4% helix, 12% strand | Q12968 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.43 | 0.77 | 26 | empty |
| 2 | 137 | 0.39 | 0.73 | 25 | empty |
| 3 | 60 | 0.36 | 0.78 | 20 | empty |
Compared structures
- 2XRW · Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear… · an experimental structure of the same protein · chain A against B, TM-score 0.01
- 2XRW · Linear binding motifs for jnk and for calcineurin antagonistically control the nuclear… · an experimental structure of the same protein · chain A against B, TM-score 0.01
- 2XS0 · Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear… · an experimental structure of the same protein · chain A against B, TM-score 0.01
- 2XS0 · Linear binding motifs for jnk and for calcineurin antagonistically control the nuclear… · an experimental structure of the same protein · chain A against B, TM-score 0.01
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12968
- Elsewhere: UniProt Q12968 · AlphaFold DB Q12968
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