UniProt Q12968
Nuclear factor of activated T-cells, cytoplasmic 3 (Q12968)
Nuclear factor of activated T-cells, cytoplasmic 3 (UniProt Q12968): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12968
- Protein
- Nuclear factor of activated T-cells, cytoplasmic 3
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
5 records of Q12968 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XRW | Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of… | x-ray diffraction | B | — | — |
| 2XRW | Linear binding motifs for jnk and for calcineurin antagonistically control the nuclear shuttling of… | x-ray diffraction | B | — | — |
| 2XS0 | Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of… | x-ray diffraction | B | — | — |
| 2XS0 | Linear binding motifs for jnk and for calcineurin antagonistically control the nuclear shuttling of… | x-ray diffraction | B | — | — |
| Q12968 | AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells, cytoplasmic 3 (Q12968) | predicted | A | — | 3 (best 0.43) |
Experiment against prediction
- 2XRW chain B against the predicted model Q12968: TM-score 0.46, RMSD 1.14 Å
- 2XRW chain B against the predicted model Q12968: TM-score 0.46, RMSD 1.14 Å
- 2XS0 chain B against the predicted model Q12968: TM-score 0.33, RMSD 1.56 Å
- 2XS0 chain B against the predicted model Q12968: TM-score 0.33, RMSD 1.56 Å
Elsewhere
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