AlphaFold monomer V2.0 prediction for negative elongation factor a (Q9H3P2)

Structure

1 distinct chain · 32% helix, 7% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8W8E · human co-transcriptional RNA capping enzyme RNGTT · an experimental structure of the same protein · chain A against U, TM-score 0.34
• 8UHD · Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated · an experimental structure of the same protein · chain A against U, TM-score 0.34
• 6GML · Structure of paused transcription complex pol II-dsif-nelf · an experimental structure of the same protein · chain A against U, TM-score 0.33
• 5L3X · Crystal structure of negative elongation factor subcomplex nelf-ac · an experimental structure of the same protein · chain A against A, TM-score 0.33
• 5L3X · Crystal structure of negative elongation factor subcomplex NELF-AC · an experimental structure of the same protein · chain A against A, TM-score 0.33
• 7PKS · Structural basis of Integrator-mediated transcription regulation · an experimental structure of the same protein · chain A against U, TM-score 0.33
• 8UHA · Structure of paused transcription complex Pol II-DSIF-NELF - tilted · an experimental structure of the same protein · chain A against U, TM-score 0.33
• 8UI0 · Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocated · an experimental structure of the same protein · chain A against U, TM-score 0.33
• 7YCX · The structure of INTAC-PEC complex · an experimental structure of the same protein · chain A against e, TM-score 0.33
• 8UHG · Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated · an experimental structure of the same protein · chain A against U, TM-score 0.33
• 8UIS · Structure of transcription complex Pol II-DSIF-NELF-TFIIS · an experimental structure of the same protein · chain A against U, TM-score 0.33
• 8RBX · Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome… · an experimental structure of the same protein · chain A against u, TM-score 0.33

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9H3P2
• Elsewhere: UniProt Q9H3P2 · AlphaFold DB Q9H3P2