MolNFT v1 · #262770 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (O00217)
O00217: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial…”. 1 pocket (best druggability 0.48). MolNFT v1 #262770 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O00217
- Type
- protein
- Length
- 210 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
- UniProt
- O00217
- Pockets
- 1 · best druggability 0.48
Structure
1 distinct chain · 37% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | protein | 210 | 37% helix, 12% strand | O00217 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.48 | 0.85 | 18 | empty |
Compared structures
- 5XTI · Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 · an experimental structure of the same protein · chain A against BB, TM-score 0.81
- 5XTH · Cryo-EM structure of human respiratory supercomplex I1III2IV1 · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against B, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00217
- Elsewhere: UniProt O00217 · AlphaFold DB O00217
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