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MolNFT v1 · #262756 · protein

AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (O75251)

O75251: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial…”. 1 pocket (best druggability 0.34). MolNFT v1 #262756 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O75251
Type
protein
Length
213 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x78A19839AffE55Dec18D3CdEEd6CFa0e8b6FDd57
Molecule
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
UniProt
O75251
Pockets
1 · best druggability 0.34

Structure

1 distinct chain · 35% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialprotein21335% helix, 10% strandO75251

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1740.340.7618empty

Compared structures

  • 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against C, TM-score 0.72
  • 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against C, TM-score 0.72
  • 5XTI · Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 · an experimental structure of the same protein · chain A against BC, TM-score 0.72
  • 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against C, TM-score 0.72
  • 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against C, TM-score 0.72
  • 5XTH · Cryo-EM structure of human respiratory supercomplex I1III2IV1 · an experimental structure of the same protein · chain A against C, TM-score 0.72

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