UniProt O75251
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (O75251)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (UniProt O75251), EC 1.6.5.3, 1.6.99.3: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability…
- UniProt
- O75251
- Protein
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
- EC
- 1.6.5.3, 1.6.99.3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
7 records of O75251 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | C | SF4 | 5 (best 0.87) |
| 5XTB | Cryo-EM structure of human respiratory complex I matrix arm | electron microscopy | C | SF4 | — |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | C | SF4 | 5 (best 0.88) |
| 5XTD | Cryo-EM structure of human respiratory complex I | electron microscopy | C | SF4 | — |
| 5XTH | Cryo-EM structure of human respiratory supercomplex I1III2IV1 | electron microscopy | C | SF4 | 4 (best 0.88) |
| 5XTI | Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | electron microscopy | C, BC | SF4 | 3 (best 0.88) |
| O75251 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 7… | predicted | A | — | 1 (best 0.34) |
Ligands
- SF4 · Iron/sulfur cluster · in 6 records
Experiment against prediction
- 5XTB chain C against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
- 5XTB chain C against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
- 5XTD chain C against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
- 5XTI chain BC against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
- 5XTD chain C against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
- 5XTI chain C against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
- 5XTH chain C against the predicted model O75251: TM-score 0.97, RMSD 0.98 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.