MolNFT v1 · #262678 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (O75306)
O75306: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial…”. 2 pockets (best druggability 0.31). MolNFT v1 #262678 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O75306
- Type
- protein
- Length
- 463 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
- UniProt
- O75306
- Pockets
- 2 · best druggability 0.31
Structure
1 distinct chain · 45% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | protein | 463 | 45% helix, 11% strand | O75306 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.31 | 0.73 | 14 | empty |
| 2 | 60 | 0.30 | 0.75 | 15 | empty |
Compared structures
- 5XTI · Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 · an experimental structure of the same protein · chain A against Q, TM-score 0.90
- 5XTH · Cryo-EM structure of human respiratory supercomplex I1III2IV1 · an experimental structure of the same protein · chain A against Q, TM-score 0.90
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against Q, TM-score 0.90
- 5XTD · Cryo-EM structure of human respiratory complex I · an experimental structure of the same protein · chain A against Q, TM-score 0.90
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against Q, TM-score 0.82
- 5XTB · Cryo-EM structure of human respiratory complex I matrix arm · an experimental structure of the same protein · chain A against Q, TM-score 0.82
- 5XTC · Cryo-EM structure of human respiratory complex I transmembrane arm · an experimental structure of the same protein · chain A against Q, TM-score 0.09
- 5XTC · Cryo-EM structure of human respiratory complex I transmembrane arm · an experimental structure of the same protein · chain A against Q, TM-score 0.09
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75306
- Elsewhere: UniProt O75306 · AlphaFold DB O75306
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