MolNFT v1 · #262501 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (Q7TMF3)
Q7TMF3: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (Q7TMF3)”. 1 pocket (best druggability 0.45). MolNFT v1 #262501 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q7TMF3
- Type
- protein
- Length
- 145 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
- Molecule
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
- UniProt
- Q7TMF3
- Pockets
- 1 · best druggability 0.45
Structure
1 distinct chain · 25% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | protein | 145 | 25% helix, 12% strand | Q7TMF3 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 144 | 0.45 | 0.77 | 25 | empty |
Compared structures
- 8OM1 · Mitochondrial complex I from Mus musculus in the active state · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 8RGT · Open Complex I from murine brain · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 7B93 · Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at… · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 8RGQ · Open Complex I from murine liver · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against q1, TM-score 0.97
- 8PW5 · CS respirasome from murine liver · an experimental structure of the same protein · chain A against q1, TM-score 0.97
- 8OLT · Mitochondrial complex I from Mus musculus in the active state bound with piericidin A · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 8PW7 · A respirasome from murine liver · an experimental structure of the same protein · chain A against q1, TM-score 0.97
- 8RGP · Closed Complex I from murine brain · an experimental structure of the same protein · chain A against q, TM-score 0.97
- 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A · an experimental structure of the same protein · chain A against q, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7TMF3
- Elsewhere: UniProt Q7TMF3 · AlphaFold DB Q7TMF3
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