MolNFT v1 · #262460 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (P42029)
P42029: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (P42029)”. 1 pocket (best druggability 0.29). MolNFT v1 #262460 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P42029
- Type
- protein
- Length
- 172 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8DD805493e22E8987a3BbCDFeD5cc3a28Cd35b3f
- Molecule
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
- UniProt
- P42029
- Pockets
- 1 · best druggability 0.29
Structure
1 distinct chain · 51% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | protein | 172 | 51% helix, 1% strand | P42029 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.29 | 0.74 | 15 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 7R4G · Bovine complex I in the presence of IM1761092, slack class ii (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7R46 · Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7QSO · Bovine complex I in lipid nanodisc, state 3 (slack) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7QSO · Bovine complex I in lipid nanodisc, State 3 (Slack) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7R4F · Bovine complex I in the presence of IM1761092, slack class i (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7R4C · Bovine complex I in the presence of IM1761092, deactive class v (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7R4D · Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7R47 · Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 8Q4A · Outward-facing, open1 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7QSM · Bovine complex I in lipid nanodisc, Deactive-ligand (composite) · an experimental structure of the same protein · chain A against X, TM-score 0.97
- 7R48 · Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) · an experimental structure of the same protein · chain A against X, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42029
- Elsewhere: UniProt P42029 · AlphaFold DB P42029
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