GL1X · GenesisL1 explorer

MolNFT v1 · #261555 · protein

AlphaFold monomer V2.0 prediction for nucleoside diphosphate kinase (O51419)

O51419: “AlphaFold monomer V2.0 prediction for nucleoside diphosphate kinase (O51419)”. 1 pocket (best druggability 0.58). MolNFT v1 #261555 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O51419
Type
protein
Length
167 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
Molecule
Nucleoside diphosphate kinase
UniProt
O51419
Pockets
1 · best druggability 0.58

Structure

1 distinct chain · 49% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANucleoside diphosphate kinaseprotein16749% helix, 17% strandO51419

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11680.580.8229empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 4DZ6 · Transition state mimic of nucleoside-diphosphate kinase from borrelia burgdorferi with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
  • 4DZ6 · Transition state mimic of nucleoside-diphosphate kinase from borrelia burgdorferi with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
  • 4DI6 · Crystal structure of nucleoside-diphosphate kinase from borrelia burgdorferi · an experimental structure of the same protein · chain A against E, TM-score 0.98
  • 4DI6 · crystal structure of nucleoside-diphosphate kinase from Borrelia burgdorferi · an experimental structure of the same protein · chain A against E, TM-score 0.98

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