MolNFT v1 · #260510 · protein

AlphaFold monomer V2.0 prediction for nucleoporin NDC1 (Q7SZC5)

Q7SZC5: “AlphaFold monomer V2.0 prediction for nucleoporin NDC1 (Q7SZC5)”. 9 pockets (best druggability 0.77). MolNFT v1 #260510 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q7SZC5
Type: protein
Length: 671 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x927Dca1Cb01AabDcD7D05D93F2C57435a5C5C603
Molecule: Nucleoporin NDC1
UniProt: Q7SZC5
Pockets: 9 · best druggability 0.77

Structure

1 distinct chain · 61% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoporin NDC1	protein	671	61% helix, 1% strand	Q7SZC5

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1086	0.77	0.79	72	empty
2	179	0.56	0.81	24	empty
3	130	0.44	0.76	21	empty
4	61	0.43	0.82	16	empty
5	96	0.41	0.76	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7SZC5
Elsewhere: UniProt Q7SZC5 · AlphaFold DB Q7SZC5

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