MolNFT v1 · #260188 · protein
AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 5 (Q9HCD5)
Q9HCD5: “AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 5 (Q9HCD5)”. 2 pockets (best druggability 0.49). MolNFT v1 #260188 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9HCD5
- Type
- protein
- Length
- 579 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
- Molecule
- Nuclear receptor coactivator 5
- UniProt
- Q9HCD5
- Pockets
- 2 · best druggability 0.49
Structure
1 distinct chain · 36% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear receptor coactivator 5 | protein | 579 | 36% helix, 5% strand | Q9HCD5 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 150 | 0.49 | 0.78 | 20 | empty |
| 2 | 152 | 0.40 | 0.74 | 18 | empty |
Compared structures
- 1V95 · Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 1V95 · Solution structure of anticodon binding domain from nuclear receptor coactivator 5 (human… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2J7X · Structure of estradiol-bound estrogen receptor beta lbd in complex with lxxll motif from… · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 2J7X · Structure of estradiol-bound estrogen receptor beta lbd in complex with lxxll motif from… · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 2J7Y · Structure of 17-epiestriol-bound estrogen receptor beta lbd in complex with lxxll motif… · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 2J7Y · Structure of 17-epiestriol-bound estrogen receptor beta lbd in complex with lxxll motif… · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 4ZI1 · Human estrogen receptor beta ligand-binding domain in complex with KB095285 and CIA12… · an experimental structure of the same protein · chain A against B, TM-score 0.01
- 4ZI1 · Human estrogen receptor beta ligand-binding domain in complex with KB095285 and CIA12… · an experimental structure of the same protein · chain A against B, TM-score 0.01
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HCD5
- Elsewhere: UniProt Q9HCD5 · AlphaFold DB Q9HCD5
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