UniProt Q9HCD5
Nuclear receptor coactivator 5 (Q9HCD5)
Nuclear receptor coactivator 5 (UniProt Q9HCD5): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9HCD5
- Protein
- Nuclear receptor coactivator 5
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
9 records of Q9HCD5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1V95 | Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637… | solution nmr | A | — | — |
| 1V95 | Solution structure of anticodon binding domain from nuclear receptor coactivator 5 (human KIAA1637… | solution nmr | A | — | — |
| 2J7X | Structure of estradiol-bound estrogen receptor beta lbd in complex with lxxll motif from NCOA5 | x-ray diffraction | B | — | — |
| 2J7X | Structure of estradiol-bound estrogen receptor beta lbd in complex with lxxll motif from NCOA5 | x-ray diffraction | B | — | — |
| 2J7Y | Structure of 17-epiestriol-bound estrogen receptor beta lbd in complex with lxxll motif from NCOA5 | x-ray diffraction | B | — | — |
| 2J7Y | Structure of 17-epiestriol-bound estrogen receptor beta lbd in complex with lxxll motif from NCOA5 | x-ray diffraction | B | — | — |
| 4ZI1 | Human estrogen receptor beta ligand-binding domain in complex with KB095285 and CIA12 coactivator… | x-ray diffraction | B | — | — |
| 4ZI1 | Human estrogen receptor beta ligand-binding domain in complex with KB095285 and CIA12 coactivator… | x-ray diffraction | B | — | — |
| Q9HCD5 | AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 5 (Q9HCD5) | predicted | A | — | 2 (best 0.49) |
Experiment against prediction
- 4ZI1 chain B against the predicted model Q9HCD5: TM-score 0.84, RMSD 0.24 Å
- 4ZI1 chain B against the predicted model Q9HCD5: TM-score 0.84, RMSD 0.24 Å
- 1V95 chain A against the predicted model Q9HCD5: TM-score 0.83, RMSD 1.92 Å
- 1V95 chain A against the predicted model Q9HCD5: TM-score 0.83, RMSD 1.92 Å
- 2J7Y chain B against the predicted model Q9HCD5: TM-score 0.72, RMSD 0.39 Å
- 2J7Y chain B against the predicted model Q9HCD5: TM-score 0.72, RMSD 0.39 Å
- 2J7X chain B against the predicted model Q9HCD5: TM-score 0.60, RMSD 1.14 Å
- 2J7X chain B against the predicted model Q9HCD5: TM-score 0.60, RMSD 1.14 Å
Elsewhere
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