MolNFT v1 · #260128 · protein
AlphaFold monomer V2.0 prediction for nck-associated protein 1 (Q9Y2A7)
Q9Y2A7: “AlphaFold monomer V2.0 prediction for nck-associated protein 1 (Q9Y2A7)”. 16 pockets (best druggability 0.79). MolNFT v1 #260128 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y2A7
- Type
- protein
- Length
- 1,128 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40ceAE928a79502748126799cBFF9492DaA1C4BA
- Molecule
- Nck-associated protein 1
- UniProt
- Q9Y2A7
- Pockets
- 16 · best druggability 0.79
Structure
1 distinct chain · 71% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nck-associated protein 1 | protein | 1128 | 71% helix, 3% strand | Q9Y2A7 |
Pockets
16 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1091 | 0.79 | 0.81 | 56 | empty |
| 2 | 226 | 0.58 | 0.79 | 34 | empty |
| 3 | 139 | 0.53 | 0.80 | 23 | empty |
| 4 | 92 | 0.49 | 0.82 | 17 | empty |
| 5 | 132 | 0.48 | 0.78 | 23 | empty |
Compared structures
- 7USE · Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 7USD · Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 7USC · Cryo-EM structure of WAVE Regulatory Complex · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 3P8C · Structure and control of the actin regulatory wave complex · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 3P8C · Structure and Control of the Actin Regulatory WAVE Complex · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 4N78 · The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton · an experimental structure of the same protein · chain A against B, TM-score 0.95
- 4N78 · The wave regulatory complex links diverse receptors to the actin cytoskeleton · an experimental structure of the same protein · chain A against B, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y2A7
- Elsewhere: UniProt Q9Y2A7 · AlphaFold DB Q9Y2A7
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