UniProt Q9Y2A7
Nck-associated protein 1 (Q9Y2A7)
Nck-associated protein 1 (UniProt Q9Y2A7): 7 experimental structures and 1 predicted model on GenesisL1, 50 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y2A7
- Protein
- Nck-associated protein 1
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 50 · 4 records with a druggable one
Structures
8 records of Q9Y2A7 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P8C | Structure and Control of the Actin Regulatory WAVE Complex | x-ray diffraction | B | — | — |
| 3P8C | Structure and control of the actin regulatory wave complex | x-ray diffraction | B | — | — |
| 4N78 | The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton | x-ray diffraction | B | — | — |
| 4N78 | The wave regulatory complex links diverse receptors to the actin cytoskeleton | x-ray diffraction | B | — | — |
| 7USC | Cryo-EM structure of WAVE Regulatory Complex | electron microscopy | B | — | 10 (best 0.88) |
| 7USD | Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex | electron microscopy | B | — | 12 (best 0.88) |
| 7USE | Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site | electron microscopy | B | — | 12 (best 0.87) |
| Q9Y2A7 | AlphaFold monomer V2.0 prediction for nck-associated protein 1 (Q9Y2A7) | predicted | A | — | 16 (best 0.79) |
Experiment against prediction
- 3P8C chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 0.98 Å
- 3P8C chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 0.98 Å
- 7USC chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 0.98 Å
- 4N78 chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 1.02 Å
- 4N78 chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 1.02 Å
- 7USD chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 1.13 Å
- 7USE chain B against the predicted model Q9Y2A7: TM-score 0.99, RMSD 1.17 Å
Elsewhere
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