MolNFT v1 · #260013 · protein
AlphaFold monomer V2.0 prediction for nuclear cap-binding protein subunit 1 (Q3UYV9)
Q3UYV9: “AlphaFold monomer V2.0 prediction for nuclear cap-binding protein subunit 1 (Q3UYV9)”. 12 pockets (best druggability 0.75). MolNFT v1 #260013 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q3UYV9
- Type
- protein
- Length
- 790 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Nuclear cap-binding protein subunit 1
- UniProt
- Q3UYV9
- Pockets
- 12 · best druggability 0.75
Structure
1 distinct chain · 68% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear cap-binding protein subunit 1 | protein | 790 | 68% helix, 1% strand | Q3UYV9 |
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 561 | 0.75 | 0.82 | 59 | empty |
| 2 | 70 | 0.69 | 0.95 | 22 | empty |
| 3 | 189 | 0.63 | 0.84 | 29 | empty |
| 4 | 308 | 0.57 | 0.76 | 39 | empty |
| 5 | 134 | 0.45 | 0.77 | 23 | empty |
Compared structures
- 3UL0 · Mouse importin alpha: mouse CBP80Y8D cNLS complex · an experimental structure of the same protein · chain A against C, TM-score 0.02
- 3UL0 · Mouse importin alpha: mouse CBP80Y8D cnls complex · an experimental structure of the same protein · chain A against C, TM-score 0.02
- 3UKZ · Mouse importin alpha: mouse CBP80 cnls complex · an experimental structure of the same protein · chain A against C, TM-score 0.02
- 3UKZ · Mouse importin alpha: mouse CBP80 cNLS complex · an experimental structure of the same protein · chain A against C, TM-score 0.02
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3UYV9
- Elsewhere: UniProt Q3UYV9 · AlphaFold DB Q3UYV9
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