MolNFT v1 · #259821 · protein

AlphaFold monomer V2.0 prediction for nibrin (O60934)

O60934: “AlphaFold monomer V2.0 prediction for nibrin (O60934)”. 6 pockets (best druggability 0.57). MolNFT v1 #259821 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O60934
Type: protein
Length: 754 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9F605311B7e26e76340423EfAfbE5e2EFc7A0b7C
Molecule: Nibrin
UniProt: O60934
Pockets: 6 · best druggability 0.57

Structure

1 distinct chain · 18% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nibrin	protein	754	18% helix, 10% strand	O60934

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	119	0.57	0.84	22	empty
2	273	0.52	0.75	33	empty
3	207	0.47	0.75	25	empty
4	82	0.45	0.81	16	empty
5	140	0.43	0.75	18	empty

Compared structures

7SID · Human atm dimer bound to NBS1 · an experimental structure of the same protein · chain A against B, TM-score 0.01
5WQD · Crystal structure of TRF2 trfh in complex with an NBS1 peptide · an experimental structure of the same protein · chain A against H, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60934
Elsewhere: UniProt O60934 · AlphaFold DB O60934

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