MolNFT v1 · #259720 · protein
AlphaFold monomer V2.0 prediction for neuron navigator 2 (Q8IVL1)
Q8IVL1: “AlphaFold monomer V2.0 prediction for neuron navigator 2 (Q8IVL1)”. 9 pockets (best druggability 0.69). MolNFT v1 #259720 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IVL1
- Type
- protein
- Length
- 2,488 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Neuron navigator 2
- UniProt
- Q8IVL1
- Pockets
- 9 · best druggability 0.69
Structure
1 distinct chain · 18% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuron navigator 2 | protein | 2488 | 18% helix, 2% strand | Q8IVL1 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 583 | 0.69 | 0.78 | 45 | empty |
| 2 | 234 | 0.53 | 0.77 | 46 | empty |
| 3 | 301 | 0.53 | 0.74 | 36 | empty |
| 4 | 178 | 0.44 | 0.74 | 24 | empty |
| 5 | 102 | 0.42 | 0.78 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2YRN · Solution structure of the CH domain from Human Neuron navigator 2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2YRN · Solution structure of the ch domain from human neuron navigator 2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IVL1
- Elsewhere: UniProt Q8IVL1 · AlphaFold DB Q8IVL1
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