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AlphaFold monomer V2.0 prediction for neuron navigator 2 (Q8IVL1)

Analyse AlphaFold monomer V2.0 prediction for neuron navigator 2 (Q8IVL1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8IVL1
Type
protein
Length
2,488 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
Molecule
Neuron navigator 2
UniProt
Q8IVL1
Pockets
9 · best druggability 0.69

Structure

1 distinct chain · 18% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANeuron navigator 2protein248818% helix, 2% strandQ8IVL1

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15830.690.7845empty
22340.530.7746empty
33010.530.7436empty
41780.440.7424empty
51020.420.7818empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 2YRN · Solution structure of the CH domain from Human Neuron navigator 2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
  • 2YRN · Solution structure of the ch domain from human neuron navigator 2 · an experimental structure of the same protein · chain A against A, TM-score 0.05

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