MolNFT v1 · #259660 · protein
AlphaFold monomer V2.0 prediction for N-terminal acetyltransferase a complex subunit NAT1 (P12945)
P12945: “AlphaFold monomer V2.0 prediction for N-terminal acetyltransferase a complex subunit NAT1 (P12945)”. 7 pockets (best druggability 0.76). MolNFT v1 #259660 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P12945
- Type
- protein
- Length
- 854 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x537a7697cdcd278751bf40d02a88e497634048D7
- Molecule
- N-terminal acetyltransferase a complex subunit NAT1
- UniProt
- P12945
- Pockets
- 7 · best druggability 0.76
Structure
1 distinct chain · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | N-terminal acetyltransferase a complex subunit NAT1 | protein | 854 | 75% helix, 0% strand | P12945 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 950 | 0.76 | 0.79 | 67 | empty |
| 2 | 137 | 0.43 | 0.76 | 23 | empty |
| 3 | 126 | 0.39 | 0.74 | 19 | empty |
| 4 | 87 | 0.36 | 0.76 | 17 | empty |
| 5 | 61 | 0.31 | 0.75 | 15 | empty |
Compared structures
- 6HD7 · Cryo-EM structure of the ribosome-NatA complex · an experimental structure of the same protein · chain A against t, TM-score 0.94
- 6HD5 · Cryo-EM structure of the ribosome-nata complex · an experimental structure of the same protein · chain A against t, TM-score 0.94
- 6HD5 · Cryo-EM structure of the ribosome-NatA complex · an experimental structure of the same protein · chain A against t, TM-score 0.94
- 4XNH · Crystal structure of yeast N-terminal acetyltransferase NatE (IP6) in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4XNH · Crystal structure of yeast N-terminal acetyltransferase nate (IP6) in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 4HNW · The nata acetyltransferase complex bound to inositol hexakisphosphate · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 4HNW · The NatA Acetyltransferase Complex Bound To Inositol Hexakisphosphate · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 4XPD · Crystal structure of yeast N-terminal acetyltransferase nate (ppgpp) in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 4XPD · Crystal structure of yeast N-terminal acetyltransferase NatE (ppGpp) in complex with a… · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 4Y49 · Crystal structure of yeast N-terminal acetyltransferase (ppgpp) nate in complex with a… · an experimental structure of the same protein · chain A against G, TM-score 0.88
- 4Y49 · Crystal structure of yeast N-terminal acetyltransferase (ppGpp) NatE in complex with a… · an experimental structure of the same protein · chain A against G, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12945
- Elsewhere: UniProt P12945 · AlphaFold DB P12945
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