MolNFT v1 · #256225 · protein
AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 2 (Q8K596)
Q8K596: “AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 2 (Q8K596)”. 15 pockets (best druggability 0.77). MolNFT v1 #256225 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8K596
- Type
- protein
- Length
- 921 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
- Molecule
- SODIUM/CALCIUM exchanger 2
- UniProt
- Q8K596
- Pockets
- 15 · best druggability 0.77
Structure
1 distinct chain · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/CALCIUM exchanger 2 | protein | 921 | 46% helix, 17% strand | Q8K596 |
Pockets
15 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 913 | 0.77 | 0.80 | 78 | empty |
| 2 | 230 | 0.67 | 0.84 | 46 | empty |
| 3 | 525 | 0.65 | 0.77 | 43 | empty |
| 4 | 260 | 0.59 | 0.79 | 28 | empty |
| 5 | 259 | 0.58 | 0.79 | 36 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8K596
- Elsewhere: UniProt Q8K596 · AlphaFold DB Q8K596
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