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AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 2 (Q8K596)

Analyse AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 2 (Q8K596) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8K596
Type
protein
Length
921 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
Molecule
SODIUM/CALCIUM exchanger 2
UniProt
Q8K596
Pockets
15 · best druggability 0.77

Structure

1 distinct chain · 46% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASODIUM/CALCIUM exchanger 2protein92146% helix, 17% strandQ8K596

Pockets

15 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19130.770.8078empty
22300.670.8446empty
35250.650.7743empty
42600.590.7928empty
52590.580.7936empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

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