MolNFT v1 · #255631 · protein

AlphaFold monomer V2.0 prediction for unconventional myosin-viib (Q99MZ6)

Q99MZ6: “AlphaFold monomer V2.0 prediction for unconventional myosin-viib (Q99MZ6)”. 20 pockets (best druggability 0.82). MolNFT v1 #255631 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q99MZ6
Type: protein
Length: 2,113 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
Molecule: Unconventional myosin-viib
UniProt: Q99MZ6
Pockets: 20 · best druggability 0.82

Structure

1 distinct chain · 47% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Unconventional myosin-viib	protein	2113	47% helix, 15% strand	Q99MZ6

Pockets

20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1077	0.82	0.83	91	empty
2	676	0.72	0.78	53	empty
3	745	0.70	0.77	45	empty
4	458	0.67	0.79	54	empty
5	693	0.67	0.76	70	empty

Compared structures

5F3Y · Crystal Structure of Myo7b N-MyTH4-FERM-SH3 in complex with Anks4b CEN · an experimental structure of the same protein · chain A against A, TM-score 0.26
5F3Y · Crystal structure of MYO7B N-MYTH4-ferm-SH3 in complex with ANKS4B cen · an experimental structure of the same protein · chain A against A, TM-score 0.26

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99MZ6
Elsewhere: UniProt Q99MZ6 · AlphaFold DB Q99MZ6

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