GL1X · GenesisL1 explorer

MolNFT v1 · #255513 · protein

AlphaFold monomer V2.0 prediction for myosin-17 (F4K5J1)

F4K5J1: “AlphaFold monomer V2.0 prediction for myosin-17 (F4K5J1)”. 13 pockets (best druggability 0.74). MolNFT v1 #255513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
F4K5J1
Type
protein
Length
1,531 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xFfa14EF9812cbceCFF953A0e1f923941F78cc638
Molecule
Myosin-17
UniProt
F4K5J1
Pockets
13 · best druggability 0.74

Structure

1 distinct chain · 56% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMyosin-17protein153156% helix, 9% strandF4K5J1

Pockets

13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1770.740.9825empty
25040.710.8056empty
34580.700.8062empty
43840.620.7844empty
53610.600.7746empty

Compared structures

  • 7KFL · Crystal structure of the cargo-binding domain from the plant class XI myosin (MyoXIk) · an experimental structure of the same protein · chain A against A, TM-score 0.22
  • 7KFL · Crystal structure of the cargo-binding domain from the plant class XI myosin (myoxik) · an experimental structure of the same protein · chain A against A, TM-score 0.22

Analyse

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