GL1X · GenesisL1 explorer

MolNFT v1 · #254882 · protein

AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 4E-binding protein mextli (Q9VR35)

Q9VR35: “AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 4E-binding protein mextli…”. 1 pocket (best druggability 0.43). MolNFT v1 #254882 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9VR35
Type
protein
Length
653 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
Molecule
Eukaryotic translation initiation factor 4E-binding protein mextli
UniProt
Q9VR35
Pockets
1 · best druggability 0.43

Structure

1 distinct chain · 27% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AEukaryotic translation initiation factor 4E-binding protein mextliprotein65327% helix, 6% strandQ9VR35

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11520.430.7518empty

Compared structures

  • 5ABV · Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli · an experimental structure of the same protein · chain A against B, TM-score 0.09
  • 5ABV · Complex of D. melanogaster EIF4E with the 4E-binding protein mextli · an experimental structure of the same protein · chain A against B, TM-score 0.09
  • 5ABU · Complex of D. melanogaster EIF4E with the 4E-binding protein mextli and cap analog · an experimental structure of the same protein · chain A against B, TM-score 0.08
  • 5ABU · Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog · an experimental structure of the same protein · chain A against B, TM-score 0.08

Analyse

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