MolNFT v1 · #254799 · protein
AlphaFold monomer V2.0 prediction for major vault protein (Q14764)
Q14764: “AlphaFold monomer V2.0 prediction for major vault protein (Q14764)”. 6 pockets (best druggability 0.68). MolNFT v1 #254799 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q14764
- Type
- protein
- Length
- 893 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- Major vault protein
- UniProt
- Q14764
- Pockets
- 6 · best druggability 0.68
Structure
1 distinct chain · 26% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major vault protein | protein | 893 | 26% helix, 32% strand | Q14764 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 391 | 0.68 | 0.81 | 46 | empty |
| 2 | 85 | 0.40 | 0.78 | 16 | empty |
| 3 | 68 | 0.35 | 0.76 | 10 | empty |
| 4 | 76 | 0.35 | 0.75 | 17 | empty |
| 5 | 88 | 0.32 | 0.73 | 27 | empty |
Compared structures
- 1Y7X · Solution structure of a two-repeat fragment of major vault protein · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 1Y7X · Solution structure of a two-repeat fragment of major vault protein · an experimental structure of the same protein · chain A against A, TM-score 0.08
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14764
- Elsewhere: UniProt Q14764 · AlphaFold DB Q14764
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