Research workbench

AlphaFold monomer V2.0 prediction for major vault protein (Q14764)

Analyse AlphaFold monomer V2.0 prediction for major vault protein (Q14764) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q14764
Type: protein
Length: 893 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
Molecule: Major vault protein
UniProt: Q14764
Pockets: 6 · best druggability 0.68

Structure

1 distinct chain · 26% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major vault protein	protein	893	26% helix, 32% strand	Q14764

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	391	0.68	0.81	46	empty
2	85	0.40	0.78	16	empty
3	68	0.35	0.76	10	empty
4	76	0.35	0.75	17	empty
5	88	0.32	0.73	27	empty

Compared structures

1Y7X · Solution structure of a two-repeat fragment of major vault protein · an experimental structure of the same protein · chain A against A, TM-score 0.08
1Y7X · Solution structure of a two-repeat fragment of major vault protein · an experimental structure of the same protein · chain A against A, TM-score 0.08

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14764
Elsewhere: UniProt Q14764 · AlphaFold DB Q14764

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