MolNFT v1 · #254581 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A6U1B4)
A6U1B4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A6U1B4)”. 8 pockets (best druggability 0.74). MolNFT v1 #254581 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A6U1B4
- Type
- protein
- Length
- 872 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A6U1B4
- Pockets
- 8 · best druggability 0.74
Structure
1 distinct chain · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 872 | 43% helix, 18% strand | A6U1B4 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 813 | 0.74 | 0.79 | 87 | empty |
| 2 | 338 | 0.66 | 0.80 | 40 | empty |
| 3 | 433 | 0.64 | 0.77 | 52 | empty |
| 4 | 337 | 0.55 | 0.75 | 29 | empty |
| 5 | 97 | 0.40 | 0.77 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6U1B4
- Elsewhere: UniProt A6U1B4 · AlphaFold DB A6U1B4
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