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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A6U1B4)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A6U1B4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A6U1B4
Type
protein
Length
872 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xBF0D2e107Ce1EcD2C4369B042274201DB719AaAF
Molecule
DNA mismatch repair protein muts
UniProt
A6U1B4
Pockets
8 · best druggability 0.74

Structure

1 distinct chain · 43% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein mutsprotein87243% helix, 18% strandA6U1B4

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18130.740.7987empty
23380.660.8040empty
34330.640.7752empty
43370.550.7529empty
5970.400.7716empty

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