MolNFT v1 · #254379 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q045Q5)
Q045Q5: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q045Q5)”. 9 pockets (best druggability 0.69). MolNFT v1 #254379 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q045Q5
- Type
- protein
- Length
- 857 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xD655697f9Ba1bf9970411e7edCda93c66d411B1a
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q045Q5
- Pockets
- 9 · best druggability 0.69
Structure
1 distinct chain · 46% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 857 | 46% helix, 18% strand | Q045Q5 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 450 | 0.69 | 0.80 | 41 | empty |
| 2 | 578 | 0.64 | 0.75 | 50 | empty |
| 3 | 456 | 0.64 | 0.77 | 44 | empty |
| 4 | 193 | 0.49 | 0.76 | 33 | empty |
| 5 | 123 | 0.42 | 0.76 | 24 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q045Q5
- Elsewhere: UniProt Q045Q5 · AlphaFold DB Q045Q5
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