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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q045Q5)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q045Q5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q045Q5
Type
protein
Length
857 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xD655697f9Ba1bf9970411e7edCda93c66d411B1a
Molecule
DNA mismatch repair protein muts
UniProt
Q045Q5
Pockets
9 · best druggability 0.69

Structure

1 distinct chain · 46% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein mutsprotein85746% helix, 18% strandQ045Q5

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14500.690.8041empty
25780.640.7550empty
34560.640.7744empty
41930.490.7633empty
51230.420.7624empty

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