MolNFT v1 · #248834 · protein
AlphaFold monomer V2.0 prediction for inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B (A8XYX3)
A8XYX3: “AlphaFold monomer V2.0 prediction for inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B…”. 9 pockets (best druggability 0.80). MolNFT v1 #248834 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A8XYX3
- Type
- protein
- Length
- 846 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4F3500FD13628563884A773578190b4E4dCd3a28
- Molecule
- Inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B
- UniProt
- A8XYX3
- Pockets
- 9 · best druggability 0.80
Structure
1 distinct chain · 34% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B | protein | 846 | 34% helix, 20% strand | A8XYX3 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 954 | 0.80 | 0.82 | 74 | empty |
| 2 | 669 | 0.72 | 0.79 | 59 | empty |
| 3 | 243 | 0.55 | 0.77 | 27 | empty |
| 4 | 221 | 0.54 | 0.77 | 33 | empty |
| 5 | 183 | 0.51 | 0.77 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8XYX3
- Elsewhere: UniProt A8XYX3 · AlphaFold DB A8XYX3
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