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AlphaFold monomer V2.0 prediction for inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B (A8XYX3)

Analyse AlphaFold monomer V2.0 prediction for inactive cap-specific mRNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A8XYX3
Type
protein
Length
846 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4F3500FD13628563884A773578190b4E4dCd3a28
Molecule
Inactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1B
UniProt
A8XYX3
Pockets
9 · best druggability 0.80

Structure

1 distinct chain · 34% helix, 20% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AInactive cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1Bprotein84634% helix, 20% strandA8XYX3

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19540.800.8274empty
26690.720.7959empty
32430.550.7727empty
42210.540.7733empty
51830.510.7720empty

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