MolNFT v1 · #248813 · protein

AlphaFold monomer V2.0 prediction for microsomal triglyceride transfer protein large subunit (P55157)

P55157: “AlphaFold monomer V2.0 prediction for microsomal triglyceride transfer protein large subunit (P55157)”. 5 pockets (best druggability 0.81). MolNFT v1 #248813 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P55157
Type: protein
Length: 894 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x4450b8770f8579152a0dD84fBd7622763A5eC221
Molecule: Microsomal triglyceride transfer protein large subunit
UniProt: P55157
Pockets: 5 · best druggability 0.81

Structure

1 distinct chain · 33% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Microsomal triglyceride transfer protein large subunit	protein	894	33% helix, 35% strand	P55157

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	631	0.81	0.86	49	empty
2	1093	0.80	0.81	123	empty
3	256	0.75	0.88	36	empty
4	567	0.61	0.74	52	empty
5	73	0.46	0.82	22	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

6I7S · Microsomal triglyceride transfer protein · an experimental structure of the same protein · chain A against H, TM-score 0.93
6I7S · Microsomal triglyceride transfer protein · an experimental structure of the same protein · chain A against H, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55157
Elsewhere: UniProt P55157 · AlphaFold DB P55157

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