MolNFT v1 · #246504 · protein

AlphaFold monomer V2.0 prediction for protein N-lysine methyltransferase METTL21A (Q8WXB1)

Q8WXB1: “AlphaFold monomer V2.0 prediction for protein N-lysine methyltransferase METTL21A (Q8WXB1)”. 1 pocket (best druggability 0.72). MolNFT v1 #246504 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8WXB1
Type: protein
Length: 218 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x1B9Be4d3bCB04cc5b127c63c2Fbac7783eAB9839
Molecule: Protein N-lysine methyltransferase METTL21A
UniProt: Q8WXB1
Pockets: 1 · best druggability 0.72

Structure

1 distinct chain · 37% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein N-lysine methyltransferase METTL21A	protein	218	37% helix, 29% strand	Q8WXB1

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	487	0.72	0.81	59	empty

Compared structures

4LEC · Human methyltransferase-like protein 21A · an experimental structure of the same protein · chain A against A, TM-score 0.91
4LEC · Human Methyltransferase-Like Protein 21A · an experimental structure of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WXB1
Elsewhere: UniProt Q8WXB1 · AlphaFold DB Q8WXB1

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