GL1X · GenesisL1 explorer

MolNFT v1 · #245591 · protein

AlphaFold monomer V2.0 prediction for protein mini spindles (Q9VEZ3)

Q9VEZ3: “AlphaFold monomer V2.0 prediction for protein mini spindles (Q9VEZ3)”. 14 pockets (best druggability 0.75). MolNFT v1 #245591 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9VEZ3
Type
protein
Length
2,042 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
Molecule
Protein mini spindles
UniProt
Q9VEZ3
Pockets
14 · best druggability 0.75

Structure

1 distinct chain · 59% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein mini spindlesprotein204259% helix, 1% strandQ9VEZ3

Pockets

14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111470.750.7783empty
210970.700.7480empty
33040.580.7730empty
43180.540.7435empty
51110.420.7717empty

Compared structures

  • 5VJC · Tog-tubulin binding specificity promotes microtubule dynamics and mitotic spindle… · an experimental structure of the same protein · chain A against A, TM-score 0.13
  • 5VJC · TOG-tubulin binding specificity promotes microtubule dynamics and mitotic spindle… · an experimental structure of the same protein · chain A against A, TM-score 0.13
  • 4QMH · The XMAP215 family drives microtubule polymerization using a structurally diverse tog… · an experimental structure of the same protein · chain A against A, TM-score 0.11
  • 4QMH · The XMAP215 family drives microtubule polymerization using a structurally diverse TOG… · an experimental structure of the same protein · chain A against A, TM-score 0.11
  • 4Y5J · Drosophila melanogaster mini spindles TOG3 · an experimental structure of the same protein · chain A against A, TM-score 0.11
  • 4Y5J · Drosophila melanogaster Mini spindles TOG3 · an experimental structure of the same protein · chain A against A, TM-score 0.11

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