MolNFT v1 · #245060 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (P54276)
P54276: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (P54276)”. 15 pockets (best druggability 0.77). MolNFT v1 #245060 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P54276
- Type
- protein
- Length
- 1,358 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9C80B506aC88CC4745F2CFbA143f406EBbF0Cf05
- Molecule
- DNA mismatch repair protein MSH6
- UniProt
- P54276
- Pockets
- 15 · best druggability 0.77
Structure
1 distinct chain · 36% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein MSH6 | protein | 1358 | 36% helix, 15% strand | P54276 |
Pockets
15 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 604 | 0.77 | 0.83 | 74 | empty |
| 2 | 567 | 0.69 | 0.78 | 57 | empty |
| 3 | 431 | 0.68 | 0.80 | 37 | empty |
| 4 | 455 | 0.66 | 0.78 | 53 | empty |
| 5 | 393 | 0.54 | 0.73 | 51 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54276
- Elsewhere: UniProt P54276 · AlphaFold DB P54276
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