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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (P54276)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (P54276) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P54276
Type
protein
Length
1,358 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9C80B506aC88CC4745F2CFbA143f406EBbF0Cf05
Molecule
DNA mismatch repair protein MSH6
UniProt
P54276
Pockets
15 · best druggability 0.77

Structure

1 distinct chain · 36% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein MSH6protein135836% helix, 15% strandP54276

Pockets

15 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16040.770.8374empty
25670.690.7857empty
34310.680.8037empty
44550.660.7853empty
53930.540.7351empty

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