MolNFT v1 · #245056 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (E1BYJ2)

E1BYJ2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (E1BYJ2)”. 14 pockets (best druggability 0.74). MolNFT v1 #245056 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: E1BYJ2
Type: protein
Length: 1,337 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xe46e19D0C021ABB95F0f435140Dfd7217c8e6810
Molecule: DNA mismatch repair protein MSH6
UniProt: E1BYJ2
Pockets: 14 · best druggability 0.74

Structure

1 distinct chain · 37% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein MSH6	protein	1337	37% helix, 15% strand	E1BYJ2

Pockets

14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	403	0.74	0.84	53	empty
2	577	0.72	0.80	57	empty
3	680	0.72	0.78	68	empty
4	306	0.56	0.76	42	empty
5	195	0.48	0.75	36	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E1BYJ2
Elsewhere: UniProt E1BYJ2 · AlphaFold DB E1BYJ2

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