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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (E1BYJ2)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (E1BYJ2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
E1BYJ2
Type
protein
Length
1,337 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xe46e19D0C021ABB95F0f435140Dfd7217c8e6810
Molecule
DNA mismatch repair protein MSH6
UniProt
E1BYJ2
Pockets
14 · best druggability 0.74

Structure

1 distinct chain · 37% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein MSH6protein133737% helix, 15% strandE1BYJ2

Pockets

14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14030.740.8453empty
25770.720.8057empty
36800.720.7868empty
43060.560.7642empty
51950.480.7536empty

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