GL1X · GenesisL1 explorer

MolNFT v1 · #242473 · protein

AlphaFold monomer V2.0 prediction for 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (Q59028)

Q59028: “AlphaFold monomer V2.0 prediction for 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (Q59028)”. 1 pocket (best druggability 0.77). MolNFT v1 #242473 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q59028
Type
protein
Length
241 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
UniProt
Q59028
Pockets
1 · best druggability 0.77

Structure

1 distinct chain · 45% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A6-hydroxymethyl-7,8-dihydropterin pyrophosphokinaseprotein24145% helix, 17% strandQ59028

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12390.770.9144empty

Compared structures

  • 8SBU · Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii · an experimental structure of the same protein · chain A against A, TM-score 0.89
  • 8SD5 · Crystal structure of HPPK from Methanocaldococcus jannaschii · an experimental structure of the same protein · chain A against B, TM-score 0.88

Analyse

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