UniProt Q59028
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (Q59028)
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (UniProt Q59028), EC 2.7.6.3: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q59028
- Protein
- 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
- EC
- 2.7.6.3
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 3 records with a druggable one
Structures
3 records of Q59028 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8SBU | Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii | x-ray diffraction | A, B | GLC | 11 (best 0.87) |
| 8SD5 | Crystal structure of HPPK from Methanocaldococcus jannaschii | x-ray diffraction | A, B, C, D | SO4 | 10 (best 0.70) |
| Q59028 | AlphaFold monomer V2.0 prediction for 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (Q59028) | predicted | A | — | 1 (best 0.77) |
Ligands
Experiment against prediction
- 8SD5 chain B against the predicted model Q59028: TM-score 0.98, RMSD 0.70 Å
- 8SD5 chain D against the predicted model Q59028: TM-score 0.98, RMSD 0.70 Å
- 8SD5 chain A against the predicted model Q59028: TM-score 0.98, RMSD 0.92 Å
- 8SD5 chain C against the predicted model Q59028: TM-score 0.98, RMSD 0.80 Å
- 8SBU chain A against the predicted model P0AEX9: TM-score 0.63, RMSD 0.36 Å
- 8SBU chain B against the predicted model P0AEX9: TM-score 0.63, RMSD 0.49 Å
- 8SBU chain A against the predicted model Q59028: TM-score 0.37, RMSD 0.75 Å
- 8SBU chain B against the predicted model Q59028: TM-score 0.37, RMSD 0.75 Å
Elsewhere
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