MolNFT v1 · #242166 · protein
AlphaFold monomer V2.0 prediction for mannose-6-phosphate isomerase (P34948)
P34948: “AlphaFold monomer V2.0 prediction for mannose-6-phosphate isomerase (P34948)”. 3 pockets (best druggability 0.61). MolNFT v1 #242166 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P34948
- Type
- protein
- Length
- 441 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x013d37A39613599f6f82870f7F3B3DDe53b34038
- Molecule
- Mannose-6-phosphate isomerase
- UniProt
- P34948
- Pockets
- 3 · best druggability 0.61
Structure
1 distinct chain · 32% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mannose-6-phosphate isomerase | protein | 441 | 32% helix, 30% strand | P34948 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 264 | 0.61 | 0.80 | 33 | empty |
| 2 | 106 | 0.46 | 0.79 | 23 | empty |
| 3 | 55 | 0.33 | 0.77 | 12 | empty |
Compared structures
- 1PMI · Candida Albicans Phosphomannose Isomerase · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 1PMI · Candida albicans phosphomannose isomerase · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 5NW7 · Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P34948
- Elsewhere: UniProt P34948 · AlphaFold DB P34948
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