UniProt P34948
Mannose-6-phosphate isomerase (P34948)
Mannose-6-phosphate isomerase (UniProt P34948), EC 5.3.1.8: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P34948
- Protein
- Mannose-6-phosphate isomerase
- EC
- 5.3.1.8
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 13 · 4 records with a druggable one
Structures
5 records of P34948 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PMI | Candida Albicans Phosphomannose Isomerase | x-ray diffraction | A | ZN | 3 (best 0.63) |
| 1PMI | Candida albicans phosphomannose isomerase | x-ray diffraction | A | ZN | 3 (best 0.63) |
| 5NW7 | Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor | x-ray diffraction | A | ZN, 9C2 | 4 (best 0.67) |
| 5NW7 | Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor | x-ray diffraction | A | ZN, 9C2 | — |
| P34948 | AlphaFold monomer V2.0 prediction for mannose-6-phosphate isomerase (P34948) | predicted | A | — | 3 (best 0.61) |
Ligands
Experiment against prediction
- 1PMI chain A against the predicted model P34948: TM-score 0.98, RMSD 1.06 Å
- 1PMI chain A against the predicted model P34948: TM-score 0.98, RMSD 1.06 Å
- 5NW7 chain A against the predicted model P34948: TM-score 0.97, RMSD 1.44 Å
- 5NW7 chain A against the predicted model P34948: TM-score 0.97, RMSD 1.44 Å
Elsewhere
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