MolNFT v1 · #242027 · protein
AlphaFold monomer V2.0 prediction for multiple PDZ domain protein (O75970)
O75970: “AlphaFold monomer V2.0 prediction for multiple PDZ domain protein (O75970)”. 16 pockets (best druggability 0.71). MolNFT v1 #242027 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O75970
- Type
- protein
- Length
- 2,070 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x22DeA0165442d1707E30933D5954EFC9Ee6e5849
- Molecule
- Multiple PDZ domain protein
- UniProt
- O75970
- Pockets
- 16 · best druggability 0.71
Structure
1 distinct chain · 16% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Multiple PDZ domain protein | protein | 2070 | 16% helix, 23% strand | O75970 |
Pockets
16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 929 | 0.71 | 0.76 | 95 | empty |
| 2 | 410 | 0.58 | 0.75 | 37 | empty |
| 3 | 265 | 0.56 | 0.77 | 28 | empty |
| 4 | 295 | 0.54 | 0.75 | 35 | empty |
| 5 | 287 | 0.53 | 0.75 | 36 | empty |
Compared structures
- 2O2T · The crystal structure of the 1ST PDZ domain of mpdz · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2O2T · The crystal structure of the 1st PDZ domain of MPDZ · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2IWP · 12th PDZ domain of Multiple PDZ Domain Protein MPDZ · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 2IWP · 12TH PDZ domain of multiple PDZ domain protein mpdz (casp target) · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 2OPG · The crystal structure of the 10TH PDZ domain of mpdz · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2OPG · The crystal structure of the 10th PDZ domain of MPDZ · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2IWO · 12th PDZ domain of Multiple PDZ Domain Protein MPDZ · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 2IWO · 12TH PDZ domain of multiple PDZ domain protein mpdz (casp target) · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 2IWQ · 7TH PDZ domain of multiple PDZ domain protein mpdz · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2IWQ · 7th PDZ domain of Multiple PDZ Domain Protein MPDZ · an experimental structure of the same protein · chain A against A, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75970
- Elsewhere: UniProt O75970 · AlphaFold DB O75970
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